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Custom Synthesis

Custom Synthesis is an expertise service we offer from our Pharmaceutical Division, and a very significant part of our Business activity at VARDA. We assure you about the quality deliverance to your requirement, through highly skilled and experienced personnel.

Custom synthesis – Made-to-measure your specifications!

Using skills and experience acquired through our exposure, VARDA undertakes development of chemical synthesis, scale-up processes and manufacturing in industrial scale.

Innovative products customized to your requirements

With years of experienced sound know ledged know-how personnel and excellent equipment, we can tailor synthesis development, scale-up and production of chemical substances individually to customer requirements, to R&D Scale, Lab scale and Pilot Scale.

Service provider – allowing our customers to concentrate on their core activities

All over the world manufacturing companies are ensuring success through greater knowledge, thanks to a combination of short development times, low production costs and high product quality. They follow a strategy of concentrating on core business and outsourcing.

Custom synthesis is our core activity of our Pharma Business Division– our streamlined structures guarantee highflexibility, speed and close collaboration with technical specialists responsible for customer’s projects.

As a highly skilled service provider, we help our customers increase productivity and so improve their competitive position in the market place.

Technologies - Focus on state-of-the-art

The latest technologies, a comprehensive range of multi-purpose equipment and an excellent infrastructure create the right environment for our specialists to apply their expertise.

They provide ideal conditions for us to help our customers develop their products and take the burden off them.

Please find the below listed reaction capabilities / technologies that we offer.

Reaction Capabilities

We offer following reaction capabilities

ACYLATION DIAZOTIZATION HOFFMANN REARRANGEMENT
AMIDATION DIEKMANN CONDENSATION HYDROGENATION
BROMINATION FRIEDEL CRAFT'S REACTION N – ALKYLATION
BUTYL LITHIUM REACTION GRIGNARD REACTION NITRATIONS
CHLORINATION HALOGENATIONS (Br2, Pocl3, Pcl5, Socl2, Cl2) METHYLATION
CONDENSATION HETEROCYCLIC SYNTHESIS PHASE TRANSFER CATALYSIS
CYCLISATION HIGH PRESSURE 225 PSIG REDUCTION
CYANATION HIGH TEMP./HIGH VACUUM DISTILLATION SODIUM AMIDE REACTION
C - ALKYLATION HIGH TEMP.REACTION WITH HEATING OIL IN TWO LEVEL PIPING SYSTEM SAND MEYER
    VILSMEIR REACTION

 

Structure Search

This Java applet allows you to draw the substructure you are looking for and search for all the chemicals containing this structure. Java-VM and JavaScript have to be enabled in your browser!

 

You have to enable Java in your browser.

JME Keyboard Shortcuts

ESC returns to the standard editing state

atoms C, N, O, P, S, F, L (for Cl), B (for Br), I, H

bonds - for single bond, = for double bond

rings 3..8 for 3 to 8 membered rings, Ph is 1, furyl 0

groups a - COOMe, y - NO2, z - SO2NH2, t - tert. butyl

Molecule may be moved by "dragging" free space and rotated by pressing also the Shift key

Experienced People and Infrastructure

Excellent equipment and outstanding technologies are key ingredients of success but more is required for custom synthesis. A high level of expertise in chemical synthesis and sound knowledge and experience of industrial implementation are also essential. Apart from this VARDA is Associated with few finest research laboratories and organizations, to leverage on technical expertise and value generation to our costomers.

Chemical expertise – at your disposal

Our highly qualified staff, such as chemists and chemical, process and control engineers have the abilities to carry out the job that we promise in most effective and efficient way.

In interdisciplinary teams, we develop and test new ideas, methods and reactions and continually expand our know-how and range of methods.

Quality Deliverance

We offer our customers an economic alternative to costly product development, processing and manufacturing. VARDA is ideally placed to deliver the required quality at the right time.

Contract synthesis

Quality from experienced hands, chemical substances with complex structures have been produced in the plants. By providing all the facilities required to carry out complex multi-step reactions in one place and offering expertise in special technologies, we give our customers an extra competitive edge.

Contract synthesis – concentration on core business

New and small-lot products always cause problems for our customers in terms of manufacturing and capital investment costs. Contract synthesis avoids underutilized equipment and the associated fixed plant and personnel costs, while reducing or avoiding additional capital investment.

It therefore frees up resources for more important tasks and allows our customers to concentrate on their core business. Our know-how combined with the comprehensive range of equipment and excellent infrastructure available at the site enables us to manufacture even the most challenging products to customer specifications in above specified quantities – on time as agreed and at an attractive price.

Confidentiality

VARDA Biotech ensures the confidentiality of the research project as well as any research information provided by our clients. We will not make any information given by your organization, or a synthesized purified for you, to any other third party.

Please note that we perform services under the guidance of a standard or specially drafted corporate material transfer agreement

FAQ

Who can use ‘custom Synthesis’ service?

You are probably in charge of procuring standards for the bioanalytical department of your firm. You might be a forensic scientist, analytical chemist, pharmacologist or medicinal chemist, working in a drug-testing lab, clinical research firm, university or research institute. You would prefer to buy the compound you need from a catalog, but you have drawn a blank. Your study depends on the acquisition of the compound and you are prepared to invest to solve the problem, depending on your expectation and technology.

How we will quote ?

You need to ensure that the vendor has properly researched a quotation. A quote based on a search and synthesis design that misses possible routes, better labeling positions, or the availability of advanced intermediates, is worse than no quote at all. It can damage or delay your project and deny you the competitive advantage that a properly researched quote can bring you. We will assign experienced PhD chemists to do the literature search and design the synthesis for you.

You will receive your quote more quickly than the industry average. This is because we have the experience built from specializing in the types of compound we will quote. This means your request is not put in line behind time-consuming general enquiries that less focused providers might attract. In case we are unable to find the possibility of your request, we would intimate you at the earliest that, we wont be able to do this particular synthesis, this enables the client to look for other possible options for the same job avoiding further delay.

Validity of Quote

Our quote will be valid for 60 days, or longer if we are supporting your grant application. We will quote in US$(by standard) / Euro / local currency (on request). We will promise to make our best efforts to deliver the compound. In the event that we are unable to deliver, we assure you that, you will pay nothing.

How we ensure Project Progress

Progress will be closely monitored, and problems solved before they become significant, by regular peer review from all of our synthetic chemistry people.

Warranty

We promise to use our best professional efforts to make the compound and to deliver on time. If we cannot deliver a particular standard of product, we will let you know within minimum possible time, enabling you to have alternative plans on those projects. We warrant that the compound meets or exceeds the specifications stated in the Certificate of Analysis. In the event that a compound is ever found to fall below specifications, we will fix the problem without any additional charges to you, or for an insoluble problem, give you your money back.


In case you are looking for synthesizing of any API’s or Drug Intermediates.

Please do provide elaborative details about your contacts and product information. Click Here

 

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:: S E R V I C E S ::

 BIOTECH

  Custom Polyclonal &
    Monoclonal Antibodies

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 PHARMACEUTICAL

  Drug Metabolites

  Deuterium Labeled
    Compounds
 

  Drug Impurities

  Custom Synthesis

  Contract Manufacturing

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